The Science of Polyphenols

The most studied compounds in nutrition. The hardest to actually get.

01/03

Polyphenols are secondary metabolites, compounds plants produce in response to environmental stress. They are the plant's defense system: protection against UV radiation, pathogens, and oxidative damage. More than 8,000 have been identified across plant species.¹

In your body, they act as antioxidants. They donate electrons to neutralize free radicals — the unstable molecules produced as byproducts of normal metabolism that, in excess, damage cells, proteins, and DNA. This process, oxidative stress, is implicated in cardiovascular disease, neurodegeneration, metabolic dysfunction, and the cellular aging process itself.¹

For most of human history, polyphenols entered the body daily through fresh plants, wild greens, and minimally processed oils. Industrial farming, soil depletion, and food processing have reduced their concentration in the modern diet by an order of magnitude.

Today, your body needs them more than ever.

What polyphenols do.

Heart

30% fewer cardiovascular events in the largest olive oil trial ever conducted

(PREDIMED, 7,447 participants, NEJM).¹

Brain

29% lower risk of dementia-related death with daily intake.

(JAMA Network Open, 2024).²

Gut

Act as prebiotics. Feed beneficial bacteria. Reduce inflammatory markers in the colon.³

Metabolic

Lowers blood sugar. Improve insulin sensitivity. Studied in PCOS, perimenopause, and metabolic disease.⁴

Skin

Reduce systemic inflammation. Protect against oxidative damage. The work no topical can do.

Longevity

A 2009 review in Oxidative Medicine and Cellular Longevity concluded long-term polyphenol intake protects against cancer, cardiovascular disease, diabetes, and neurodegenerative disease.⁵

The polyphenols doing the work.

Polyphenol concentration is not a single number. It is a profile. Below is what each compound does, and the concentration measured in Alya by the World Olive Center for Health in Athens.

133 mg/kg

Structurally similar to ibuprofen. Inhibits COX-1 and COX-2, the same anti-inflammatory enzymes ibuprofen acts on.¹ The peppery sensation in the throat is oleocanthal binding to receptors that detect this class of compounds.

In one 15ml shot of Alya

1,876

Mg/kg total Polyphenols

3x

Approximately 14mg of hydroxytyrosol and tyrosol derivatives—Thats nearly three times the EU's threshold for the approved health claim.

These compounds exist together in the olive in a food matrix that improves bioavailability. Absorption rates of isolated polyphenols are significantly lower than the same compounds consumed in whole food form.¹

Why concentration is preserved in Alya

Polyphenol concentration in olive oil is not determined at bottling. It is determined by every condition the olive experienced from tree to vial. Each step in our process is designed to preserve what the olive made.

  • Chetoui, endemic to Tunisia. The cultivar with one of the highest naturally occurring polyphenol profiles documented in olive science.

  • Polyphenol biosynthesis in olive trees is upregulated by stress — drought, sun exposure, poor soil. Our grove is rainfed and unirrigated, producing fruit with elevated polyphenol concentrations as a stress response.

  • Polyphenol concentration in the olive fruit peaks before ripeness, then declines. We harvest at the peak. Most producers harvest later for higher oil yield.

  • Oxidation begins as soon as the fruit is crushed. We press at low temperature, within hours of harvest, to preserve the compounds.

  • Filtration removes phenolic compounds along with sediment. Alya remains unfiltered, retaining what the olive produced.

  • Polyphenols degrade under light and oxygen exposure. Every step from press to vial controls for both.

1800+

The highest certified polyphenol concentration on the U.S. market.

Alya is how you get the dose.

One ingredient: Chetoui olive oil from our family's grove in Tunisia. Third-party tested by the World Olive Center in Athens. Single origin, single variety, single harvest. Shipped within weeks of pressing.

Not a supplement. Not an extraction. Whole-food form, the way your body knows how to use it.

What you'll notice

We don't promise timelines. Bodies are not on a schedule. But here is the pattern we see across thousands of daily rituals.

Digestion shifts first. Less bloating. More regularity. A quiet sense that your gut is doing what it is supposed to do.

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By the World Olive Center for Health